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metaplastic change
Metaplastic breast cancer, also called metaplastic carcinoma of the breast, is a rare type of breast cancer. Cancer begins when normal cells in the breast begin to change and grow uncontrollably, forming a mass called a tumor. A tumor can be& ...
In simplistic terms, it is as if the original cells are not robust enough to withstand the new environment, and so they change into another type more suited to the new environment. If the stimulus that caused metaplasia is& ...
A 1.4-cm poorly differentiated metaplastic carcinoma with chondroid was removed with negative margins. This time, ER was weakly staining in 2% of cells, and PR was weakly staining in 5% of cells; HER2 remained negative.
Metaplasia is a reversible change in which one differentiated cell type (epithelial or mesenchymal) is replaced by another cell type. It may represent an adaptive substitution of cells, that are sensitive to stress by cell types better able to& ...
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